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The patent on the drug expired in multiple European countries -- Germany, the United Kingdom, Italy, the Netherlands, Switzerland, Ireland, Austria, Belgium, and Denmark -- today. Teva was already selling the drug in Spain, Canada, and a few other countries. Americans will have to wait. In 2011, Pfizer successfully defended a patent covering Suplemento bcaa efeitos colaterais do viagra method of use as an erectile dysfunction drug. The active compound was originally developed as Revatio for high blood pressure until Pfizer realized that patients taking the drug were feeling better in more than one way. Today's European launch wasn't a big surprise; the nice thing about patent expirations is that investors can see them coming and price in the reduction of sales accordingly. In the first quarter, sales in the U. were greater than all the other countries combined, so Pfizer will still enjoy about 1 billion worth of exclusive sales until April 2020. That's six months later than when the aforementioned method-of-use patent expires because Pfizer got a pediatric extension for testing Revatio in children with high blood pressure.

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THEREFORE, WE ARE CAUTIONING EACH READER OF THIS REPORT TO CAREFULLY CONSIDER THE FOLLOWING FACTORS AND CERTAIN OTHER FACTORS DISCUSSED HEREIN AND IN OTHER PAST FILINGS WITH THE SECURITIES AND EXCHANGE COMMISSION. FACTORS THAT COULD CAUSE OR CONTRIBUTE TO THE OUR ACTUAL RESULTS DIFFERING MATERIALLY FROM THOSE DISCUSSED HEREIN AND IN ANY FORWARD LOOKING STATEMENT OR FOR THE PRICE OF OUR COMMON STOCK TO BE AFFECTED ADVERSELY INCLUDE BUT ARE NOT LIMITED TO: WE HAVE A HISTORY OF OPERATING LOSSES WHICH ARE LIKELY TO CONTINUE IN THE FUTURE. Our auditors have included an explanatory paragraph in their report of Independent Public Accountants included in our audited financial statements included elsewhere in this report for the years ended December 31, 2000, 1999 as previously restated and 1998, respectively, to the effect that our losses from operations for the year ended December 31, 2000, and the working capital deficit and the retained deficit at December 31, 2000 raise substantial doubt about our ability to continue as a going concern.

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